Why is this an issue?

The comma operator takes two expressions, executes them from left to right, and returns the result of the second one. The use of this operator is generally detrimental to the readability and reliability of code, and the same effect can be achieved by other means.

i = a += 2, a + b;  // Noncompliant: What's the value of i ?

Writing each expression on its own line will improve readability and might fix misunderstandings.

a += 2;
i = a + b; // We probably expected to assign the result of the addition to i, although the previous code wasn't doing it.

Exceptions

The comma operator is tolerated:

for (i = 0, j = 5; i < 6; i++, j++) { ... }
i = (a += 2, a + b); // Compliant by exception

Resources

Documentation